CNS Regeneration

The goal of the lab:

Reconnection of disconnected parts of the brain and spinal cord

 To restore quality of life 

Centeral nervious system regeneration in Hieroglyphics

Writing a "Prescription" to
Reconnect the
Disconnected Parts of the Brain

Nano Neuro Knitting

 Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision, Proc Nat Acad Sci USA 103: 5054-5059.

 

-- Comments in:              

-Nature Materials – Nanozone news online (2006) Apr. 13     

-The Lancet Neurology (2006) May; 5(5): 386-387

-ACS Chemical Biology (2006) May; 1(3): 116

-Nature Reviews Neuroscience (2006) May; 7(5): 333

-Journal of the American Medical Association (2007) Jan.; 297(1): 31

-Technology Review (2007) Mar./Apr.; 110: 52-55

CNS-RELATED PUBLICATIONS

 

Ellis-Behnke RG and Schneider GE. “Peptide Amphiphiles and Porous Biodegradable Scaffolds for Tissue Regeneration in the Brain and Spinal Cord.” In: Biomedical Nanotechnology, Methods in Molecular Biology series, Sarah Hurst (vol. ed.), vol. 726. New York, Springer, 2011. (In press).

 

Schneider GE and Ellis-Behnke RG.  “CNS Regeneration.” In: Encyclopedia of Neuroscience, George Adelman and Barry H. Smith (eds.), 3rd ed., revised and enlarged, CD-ROM format, Amsterdam, Elsevier, 2004.

 

Ellis-Behnke RG and Jonas JB. (2011) Redefining tissue engineering for nanomedicine in ophthalmology. Acta Ophthalmol. 89: e108-14.

 

Liang YX, Chan KCW, Cheung SWH, Tay DKC, Wu EX and Ellis-Behnke RG. (2010) CNS regeneration after chronic injury using a self-assembled nano material and MEMRI for real-time in vivo monitoring. Nanomedicine DOI: 10.1016/j.nano.2010.12.001

 

Ellis-Behnke RG, Liang YX, Guo J, Tay DKC, Schneider GE, Teather LA, Wu W and So KF. (2009) Forever young: how to control the elongation, differentiation and proliferation of cells using nanotechnology. Cell Transplantation 18: 1047-1058.

 

Ellenberg D, Shi J, Jain S, Chang JH, Brady S, Melhem E, Lakkis F, Adamis A, Chen DF, Ellis-Behnke RG, Langer RS, Strittmatter S and Azar DT. (2009) Impediments to eye transplantation: ocular viability following optic nerve transection or enucleation. Br J Ophthalmol. 93: 1134-1140.

 

Ellis-Behnke RG, Teather LA, Schneider GE and So KF. (2007) Using nanotechnology to design potential therapies for CNS regeneration. Current Pharmaceutical Design 13: 2519-2528.

 

Ellis-Behnke RG. (2007) Nano Neurology and the 4 Ps of CNS Regeneration: Preserve, Permit, Promote and Plasticity. Med Clin North Am. 91: 937-62.

 

Guo J, Su H, Zeng Y, Liang YX, Ellis-Behnke RG, So KF and Wu W. (2007) Reknitting the injured spinal cord using self-assembling peptide nanofiber scaffold. Nanomedicine 3: 311-21.

 

Ellis-Behnke RG, Liang YX, You SW, Tay DKC, Zhang S, So KF and Schneider GE. (2006) Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision, Proc Nat Acad Sci USA 103: 5054-5059.

-- Comments in:              

-Nature Materials – Nanozone news online (2006) Apr. 13     

-The Lancet Neurology (2006) May; 5(5): 386-387

-ACS Chemical Biology (2006) May; 1(3): 116

-Nature Reviews Neuroscience (2006) May; 7(5): 333

-Journal of the American Medical Association (2007) Jan.; 297(1): 31

-Technology Review (2007) Mar./Apr.; 110: 52-55

 

Schneider GE, Ellis-Behnke RG, Liang YX, Kau PWF, Tay DKC and So KF. (2006) Behavioral testing and preliminary analysis of the hamster visual system. Nat Protoc.1: 1898-1905.

 

Ellis-Behnke RG, Teather LA and So KF. (2006) Molecular restoration of the body: nano neuro knitting for brain repair. J European Anti-Ageing Medicine & British Anti-Ageing Medical Journal 4: 34-35.

 

Ellis-Behnke RG, So KF and Zhang S. (2006) Molecular repair of the brain using self-assembling peptides. Chimica Oggi 24: 41-43.

 

Teather LA, Packard MG, Smith DE, Ellis-Behnke RG and Bazan NG. (2005) Differential induction of c-JUN and Fos-like proteins in rat hippocampus and dorsal striatum after training in two water maze tasks. Neurobiology of Learning and Memory 84: 75-84.